It seems unlikely for that much time to elapse before a reaction, but I would definitely consult with a veterinarian. Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. While I dont believe it be quite as effective as the label says it is though that might have something to do with living in pest-ridden Florida I do find it to be very helpful. The best thing about Seresto is how long it can do its job up to 8 months! I chose Frontline Plus for him as it seems to be an older, safer spot-on. Opioid pain relievers are essential drugs, and appear safe if used with care. Seven Collies sound like a lot of work but also very wonderful! SIMPARICA TRIO killed fleas before they could lay eggs for 35 days. Evoluciona. Mar 2013. This gave me a great start for research. Unfortunately, when we gave Vakaa his dose of Credelio, he threw it up twice actually since I wasnt able to get to him before he gobbled up some of his regurtitated food! However, I have to state the disclaimer that even parasite protection products officially labeled safe from an MDR1 standpoint should really be designated safe-ish. Most of these products are chemical compounds, and as such have more potential to cause a reaction than just, well, water. Thanks for your efforts to help! Buy Simparica Trio for Small dogs 5.1-10Kg. I will try to find the article again, I stupidly didnt bookmark it. ? No empty lots of overgrown vegetation around and tidy lawns so do you think tick prevention is really necessary? It is supposed to repel mosquitoes as well but I am very nervous about not using a heart worm preventative. Last time I took my Collies to a pet store here in parasite-infested Florida, I asked one of the clerks what they sold the most of as far as flea and tick preventives. We do, however, have lots of deer ticks (also known as black legged ticks). Options: 3 flavors. Advantage Multi can be a great product when used with care, and I would expect the same to be true for Advocate. The oral chew contains a specially optimised trio of ingredients for . Thanks again for your time : ), Thank you for pointing that out! ivermectin, selamectin)? Is the Frontline the one listed in the article ok in a multi dog family where there is a risk of one licking it off the other? The flavored, chewable tablets were consumed . On the downside, its efficacy only lasts for about a day. We have an MDR1 heterozygous Aussie and this was the best breakdown of the meds we found. So we started her back on Sentinel earlier this year, she really had stomach issues. However, it is strong and can cause a skin reaction. Because of their similarity to Heartgard, Ive placed them in the same caution category. Does your veterinarian give other reasons for prescribing Credelio vs. similar brands? Thank you for your very informative article. Thank you. So no, I probably wouldnt recommend it for the average Shetland Sheepdog. IMPORTANT SAFETY INFORMATION: NexGard is for use in . My border collie started having seizures (he was on Bravecto AND Sentinel) and the vet never said anything about the gene mutation. Is hartz ultraguard ear mite treatment for dogs safe? (Your vet or a pet store associate may recommend otherwise, but bear in mind that they also want to make money.). Simparica TRIO was approved by the U.S. Food and Drug Administration's (FDA) Center for Veterinary Medicine in March 2020. Simparica Trio chewable tablets for dogs 1.25-2.5 kg Simparica Trio chewable tablets for dogs >2.5-5 kg . 1 x 40mg tablet for 22.1 to 44 pounds. In regard to natural products, Ive used some organic topicals, which Ill list later, that aresomewhat effective as repellents; but unfortunately I do not know of any natural pest control products that actually work as well as chemical-based ones. Simparica Trio Intestinal Worms & Heartworm Treatment for Dogs. As the agency explained: Although FDA scientists carefully evaluate an animal drug prior to approval, there is the potential for new information to emerge after marketing, when the product is used in a much larger population. (New drugs continue to be highly monitored for the first three years following their release.). Any thoughts on either of these? I tried Seresto with my girl and she had a seizure. Perros (mutacin del gen MDR1). In hot, flea-infested areas like where I live in Florida, Parastar Plus might not be the best option; but its definitely something I would have tried when I still lived in Michigan. I would say you are right to be concerned, and Ill give some info why. Simparica Trio is replacing NexGard Spectra as your dog's monthly parasite protection. If you can, its always a good idea to consult with a vet who is knowledgeable about MDR1 and Collies. Best of luck with your girl. If this gene is mutated, it will create a defective protein, and consequently, drugs will remain and build up in the brain to toxic levels. Hello! Unfortunately, it seems most people who lost their dogs to Seresto collars simply did not make the connection until it was too late. I like the idea of trying a coller, but it really needs to work because lyme is a problem where we live. Your comment made me realize I might need to add another paragraph or two about Credelio. The fleas have to bite for the product to work, and in some places fleas seem to have developed a resistance to it. The benefits of Simparica. Thank you. Thank you for all the research, it was all so helpful. So heres the culmination of my research: information gathered from laboratory case studies, veterinarians, and Collie owners, breeders, and exhibitors. Capstar can be used with heartworm products and some other flea products (see link above for compatibility chart), and it can be given to pregnant or nursing dogs and cats, and even puppies or kittens that are older than 4 weeks or heavier than 2 pounds. I recently saw the USA Today headline (I get notifications on my phone) about Seresto collars and made a mental note to read it later and update this article if need be then promptly forgot about it! Multi-Drug Resistance 1 (MDR1) is a gene that is meant for helping to protect the brain. The tail curling and pacing lasted over a week. And use same collar for a few months. I myself have successfully used both on my 2 Collies and my Aussie mix with no ill effects. You should still keep an eye on your pet when introducing new organic products. Demonstrated 98.9% effectiveness against existing tick infestations in 48 hours . The manufracturers website lists many different kinds of ticks, and people on this thread talk about using FrontLine for ticks. Safety has not been evaluated in pregnant, breeding or lactating dogs. Due to this fact, Pet Place warns: The MDR1 mutation is most commonly seen in herding breeds. Either Sentinel or Interceptor are generally considered safe for Collies and can be used to treat demodectic mange. I will not give anything oral to my dog, since our first collie was probably killed by heartworm preventative. Have you had any issues with Seresto? I appreciate the research in this thank you! It will make your dog smell absolutely yummy while protecting them from fleas, ticks, black flies, and mosquitoes. Thank you! I realized that I just replied to another comment from you Im sorry you and your doubly sensitive girl are having such trouble trying to find products that work for her! Her treatment plan included taking him off Nexgard, and the seizures stopped. Took that collar right off her. According to Dog Aware, most flea and tick control medications have not been found to cause adverse effects when used as directed, but toxicity can occur iftopicalproducts areingested. This is why reading labels is so important. What an awesome article. If youre hoping for a quick, easy skim and just want to know which pest protections are considered safe, Ill list those first under each heading, followed by the use with caution category, and finally the not safe options. GSD is an abbreviation for German Shepherd Dog , Thankyou so much for your articleso much great infoI have a 7 month mini Aussieon Symparticabut not feeling good about itshe hasnt been tested for MRD1 but I know I have to change it upthankyou again , Youre very welcome, and good luck with your pup! Dogs, 6 Month Supply. I have been told that Advocate is safe for him at the recommended dose. Rev. Please tell me if I am wrong. Is this true? If youre going the oral tablet route, Credelio is one I personally feel comfortable with! Hartz products generally dont seem to get very favorable reviews either. The active ingredients of SimpleGuard 3 are the same as Vectra 3D: dinotefuran, pyriproxifen, and permethrin. I say this as she is running around the room l barking and trying to dig up the coachyep, just about nap time, That is excellent news, and Im so glad to hear it! Theyre so fun and crazy at that age. I was unaware of MDR1 Mutation drug reactions at the time. Unacceptable for me) He is MDR1 clear. Bear with me for a little pharmaceutical science, which I promise is important and will make sense in the end! Frontline Plus is milder than Frontline Gold, which I wouldnt recommend for the same reason that I dont like recommending Advantix theyre too strong and have a tendency to cause skin reactions. Ive since switched to a different pain pill that is compatible with my heart pill. (Of course, skin irritation can happen with any topical product.) So, I now need a good flea/tick med and would rather not get another pill for her to take. Best of luck! One observation: You mention that Credelio has fewer reported seizures (6 in as many months) than other drugs in the isoxazaline class. The agency is asking the manufacturers to make the changes to the product labeling in order to provide veterinarians and pet owners with the information they need to make treatment decisions for each pet on an individual basis.. Matching game, word search puzzle, and hangman also available. All but one (5 of 6) of the Simparica Trio-treated dogs were negative for D. immitis antigen and MF on day 180, while the remaining dog was positive for the antigen but negative for MF for this day. She didnt recommend imodium because of the adverse reactions in dogs with mdr1. . . Of all the products you mentioned, I would prefer to try K 9 Advantix since it both repels and kills. (Also, bear in mind that the Permethrin in Zodiac Spot On will make it very dangerous, even toxic, to cats, in case you have any.) Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. Oh no! Safe in avermectin-sensitive collies and dogs with the MDR1 gene; We need more people like you. Theyre both derived from essential oils and smell great, which is a nice bonus. Two dogs were positive for D. immitis antigen but not MF on days 210 and 236. Normally I would advise to just listen to your vet, but in this case I think I have to say listen to your instincts also especially since youre the one living with your pet and making the observations. Some remain safe, others should be avoided. Sarolaner is an . It should be given with food (as should any oral medication, really) to avoid a possible upset stomach. I have a 8 yr old MAS/Aussie who is MDR1 +/+ and I have her on Trifexis and have had no issues to date. WSU is the leader in identifying drugs that may be dangerous for dogs with the MDR1 mutation and can identify alternative medications and doses. He said he himself uses Seresto collars on his Australian Shepherds, but that in his experience the collars tend to last 6 months for his fluffballs, not 8. She has always had a sensitive stomach, but as she gets older, it gets worse. The flea pills and chews all contain a pesticide called isoxazoline, the FDA said . -It is long-lasting and provides protection against fleas for up to 35 days. ), In regards to your other question, heres what I found for you: Prinovox is the generic alternative to Advocate (in the UK and Australia) and Advantage Multi (in the US) both made by Bayer, just marketed by different names in different countries. (My dogs dont groom each other or really play that way now that theyre older and settled, so I feel comfortable using topicals now.) It is safe for use with anthelmintics like heartworm meds and has no known negative drug-drug interactions. If the veterinary staff cant see they are prescribing the wrong combination of medications, maybe you can point it out to them.. , Emily, thanks for a very helpful and informative article. For dogs who have a case of mange or ear mites, the treatment can involve topical applications of compounds containing (you guessed it) Ivermectin. The MDR1 mutation is believed to occur in approximately 50% of Australian Shepherds. enough to have 4 dogs like I do! From an MDR1 standpoint, Simparica is *technically* safe; but I am leery of it considering the FDA warning about isoxazolines (-laner medications) I discussed in the article. Its simpler to identify medicines by their components, since many of them are essentially the same thing marketed under different brand names. I have a new Collie-mix with bi-coloured coat. I have called two divisions of the manufacurer trying to find out whether the products cover all the ticks they list on their website, or only the one tick of concern that they list on their packaging. It is easily administered since it is a flavored chewable, and it takes care of heartworms and fleas. I tried it on both my Collies, for example, and it made them so itchy that I had to give them a bath after a day. Ivermectin is reported safe at heartworm prevention doses but there are better drugs available. I would actually place it in the caution category, since if a dog who had an active heartworm infection was given diethylcarbamazine (Dimmitrols main ingredient) it could suffer severe side effects and even die. Vectra is a rather strong product that I wont personally recommend, as so many dogs in the Collie family have sensitivities. I give Interceptor Plus for HW, but Im conflicted about which direction to go for flea & tick. I actually ended up choosing Interceptor Plus along with Credelio after looking at your research and getting some advice from fellow Aussie owners. This is a new extensively tested product now available in Australia that provides optimal protection for your dog. How to use Simparica Trio. I know Simparica is more convenient since it means giving one monthly preventive instead of two, but the trade-off with the combo meds is that theyre usually stronger. Also, Permethrin is one of the active ingredients in K9 Advantix II, an effective spot-on product Ive used on my Aussie mix with no ill effects. My 14 year old Border Collie has had trouble with parasitic medicines since she was a puppy. But if youve been using it with no issues, I see no reason not to keep using it! Many veterinary clinics keep some in stock for their clients, and it is also available at online stores like 1-800-PET-MEDS or Chewy. Sarolaner had been approved in 2016 to treat flea and ticks, moxidectin . We gave her the first dose in late February and there were no adverse side effects for Sugar. Turns out it is also used for the treatment and prevention of roundworms and lungworm nemotodes in dogs, according to Vet Shop Max. In the meantime, no need to give heartworm meds if its still snowy where you are, so youve got some time to figure out what to do before the mosquitoes become active again! My pleasure! The accidental ingestion of the product may potentially result in . I did some digging, and from what Ive read it sounds like just one report would be considered anecdotal and would not be considered evidence that Seresto could cause seizures, but if there are 2 or more reports then the company might be obliged by the EPA to add a potential seizure warning to its label or possibly to do more clinical safety research. If you found this post helpful, you can leave me $1 or more tip on vocal.media or purchase one of our recommended dog products from Amazonso we can buy more dog supplies ourselves! Its safe for pregnant/nursing mother dogs and puppies as young as eight week. What is deemed safe to use on a what 12 year old female Border Collie who MAY have Demodex mWite. Until progress is achieved in ongoing studies, adjustments are made to the medications themselves, and the FDA warning is lifted, Ill have to leave Bravecto in the caution category. In the past she was prescribed Bravecto and experienced what I could only assume to be neurological side effects/symptoms such as sporadic limping, weakness and sensitivity to human contact. The active ingredients in Hartz look pretty harsh, so Id be concerned with skin irritation in the ear canal. I recently adopted a Collie puppy who came with a dose of Credelio and Interceptor, which I have in the past successfully used on my other 3 dogs (both Collies and the Aussie mix). The FDA issued an alert to owners and veterinarians and said it was requiring clearer labels on the products. $153.89. Simparica Trio works against the same ticks as Nexgard and also protects your dog from heartworms, hookworms, and roundworms. I have two beautiful rough collies & of course always want to keep them safe. Background: The efficacy and safety of a novel isoxazoline compound, sarolaner (Simparica , Zoetis) and spinosad (Comfortis , Elanco) as a positive control were evaluated for the treatment and control of natural flea infestations on dogs in two randomised, blinded, multi-centric clinical trials conducted in 11 veterinary clinics in northeastern and southeastern states of Australia. . (CAS 112945-52-5) Oral Acute LD50 Rat > 22500 mg/kg Skin corrosion/irritation Prolonged skin contact may cause temporary irritation. However, it would be best to have a veterinarian collect a skin scraping to examine under a microscope and determine whether skin irritation is caused by demodectic or sarcoptic mites, as the causes and treatments differ between the two types. If youre someone who lives in a tick-prone area or likes to take your dogs on woodland rambles (like me), this is a letdown. Please keep me updated if you think of it! Nothing could be done for them. To make dosing easy, it's available for dogs in six sizes based on body weight range: Gold: 2.8-5.5 pounds. Dash is MDR1 mutant/normal. Hes just a puppy himself and was already started on Interceptor and Credelio. They both have tolerated Bravecto very well.no noticeable side effects. Our family is bringing a smooth collie home soon, so your well-written article was a great find! After 1 emergency vet visit and a number of consultations with our primary care vet, we took him off simparica. Product Description. If you havent yet tried Interceptor for heartworm prevention, I would suggest that for you. Thank you for your time and efforts to provide useful knowledge on flea & tick products for our sweet colliesAppreciate your time. Given your knowledge, would you suggest Credelio vs. K9 Advantix II (if tolerated) ? Simparica Trio reduced live flea counts, as well as clinical signs of FAD, by 99.0% at day 30 and by 99.7% at day 60. . Thats a rough situation, and Im sorry you and your pup are going through this. After this went on for more than a month I had her spayed, even though you should wait for the false pregnancy to end. Is this vaccine something youve heard of? I didnt see the link for the drug compatibility. We have always used Frontline Plus, but it has recently started causing dandruff on our dog, and it makes his coat greasy. I asked the vet for an alternative and was recommended Seresto collar or Vectra 3D. 1x 20mg tablet for 11.1 to 22 pounds. I'm planning to go on a camping trip mid-September and my vet prescribed a simparica trio tablet to make sure he's safe from fleas and ticks. I got an email from the rescue agency that fussed that I hadnt given them their heartgard for this month. She had a severe reaction with diarrhea, drooling, depression etc. Effective against ticks that may carry debilitating diseases like ehrlichiosis, anaplasmosis, and rickettsiosis 2. The bottom line is, its best to avoid giving your Collie Heartgard or a similar medication. FDA-approved to block the pathogen that may cause Lyme disease by killing deer ticks. Dogs with the mutation lack a protein (P-glycoprotein) which is responsible for pumping the drugs from the brain. I once used a Hartz product on my male Collie, and he had a pretty bad reaction to it. Thanks much for the info before I bought anything! Your article has been very helpful in my quest to help my forest loving dog stay safe from tics. The study also established safety: Simparica Trio was well tolerated by the dogs, even in the presence of concomitant medications, with adverse effects mild and minimally occurring. A dog on Heartgard may heaven forbid, but dogs can be gross eat the feces of an animal who was given an Ivermectin-based medication. Thankfully he recovered but my vet tells me Interceptor Plus is safe and he must have ingested something on his walk. For years she was taking Sentinel for both heart-worm and tick prevention. The US Food and Drug Administration (FDA) issued a warning on September 20, 2018 about the isoxazoline flea and tick products fluralaner for dogs and cats (Bravecto), afoxalaner for dogs (Nexgard), and saroloner for dogs (Simparica). As with any topical, of course keep an eye out for skin irritation. It just depends on the individual dog. Safety. Emily is an avid writer, blogger, and Collie lover who collects and posts stories about Collies from around the world. Selamectin is their shared main ingredient. Besides safety, Revolution is an attractive option because of its ease of application (topical squeeze-on tube) and versatility in treating heartworm, fleas, dog ticks, sarcoptic mange, and even ear mites. Hi Debbie! The drawback of using them is that they generally dont take care of as large a range of parasites as using two separate medications does. Since I recommend being careful about using Simparica, I would be even more careful about using the more potent Simparica Trio. (Just bear in mind that Preventic contains amitraz, which is toxic to cats.). Hi Emily, do you know if panacure is a safe wormer? . Of course, I do have to state the disclaimer that theres no guarantee with any product that it wont cause a reaction, but it sounds like youre doing a good job of monitoring your girl after giving her anything. However, as it is the amped-up version of Frontline Plus and contains 3 active ingredients, its always wise to check the application site for adverse skin reactions. Simparica Trio Dosage. I actually just updated the section on Seresto collars today with new info and a link to a USA Today article about side effects resulting in seizures and even death. Thank you for writing this article. After 24 hours, it is considered waterproof and a bath, while alleviating some effects, will not offer as much relief. Hope this helps! For me, every medicine has its side effects, and it really comes down to weighing the risk of side effects against the risks posed by parasites. Key Features of Simparica Trio. Australian Shepherds have a slightly lower incidence, with 50% being affected . . This year she has a very high degree of irritation when applied (I had to wash it off). (There are other places, but none more affordable that Ive found.) As with any topical product, monitor your pet for signs of skin irritation, and give them a bath within 24 hours to wash it off if signs of irritation are seen. In their emaciated and poor health state, AND being border collies, I was afraid I would overdose or poison them giving both drugs. Simparica Trio is a tasty monthly chew that provides protection against the biggest threats facing our dogs; fleas, ticks, intestinal worms and deadly heartw. No toxicity was seen when affected dogs were given 28 to 35.5 mcg/kg monthly for one year. It is also used off-label to control sarcoptic mange and demodectic mange. Many Rough Collie owners swear by them, and one owner mentioned that she lives in the woods and the Seresto collars kept the ticks off her Roughs. In FL resistance is bad, and we split our time between FL & NJ. Also what can be used for giardia? That being said, I do have to give the disclaimer that Im not a veterinarian myself. Capstar specifically targets adult fleas, so it is best paired with a product like Sentinel. I cant claim to have all the answers, and my goal with this article was simply to make a fairly comprehensive guide to help each pet owner make an informed decision in tandem with their veterinarian. I just picked out a beautiful tri color rough collie this morning! Negative reactions such as vomiting, diarrhea, and tremors were only observed at supratherapeutic (higher than recommended) doses. You might want to look at the information on Nexgard. Wash hands after handling the product. Eliminate fleas before they lay eggs. In a wellcontrolled 60day US field study conducted in dogs with existing flea infestations of varying severity, the effectiveness of SIMPARICA TRIO against fleas on Day 30 and 60 visits was 99.0% and 99.7%, respectively, As long as I remember to apply it at least once weekly, Ive found it to be very effective. There weren't as many seizures reported as with Nexgard, but it did have several more reported than Bravecto. In a laboratory study, the product was well tolerated in dogs with a deficient multidrug-resistance- protein 1 (MDR1 -/-) following single oral administration at 3 times the recommended dose. (Theres also a hyperlink to her article.) Dogs with the MDR1 mutation can be 200 times more sensitive to the drugs than dogs that do not have this mutation. . Sugar is almost 4 months old now! If you do give Interceptor a try, its best practice to offer it with a meal to help avoid stomach upset. Im leaning toward Frontline Plus based on what you wrote. The login page will open in a new tab. Ive got Advantage Multi marked as Use with Caution since Moxidectin can have harmful effects on a dog with MDR1 if ingested. Documented negative reactions were only provoked at higher-than-normal dosages and were comparatively mild, consisting of salivation, ataxia (dilated pupils), and depression. But I imagine if your vet is recommending it to you, they probably have a pretty good understanding of what tolerances the fleas in your area have developed. And safe travels to you and Lola in the future. Unless youre, say, an expat living in China, you can definitely find a better option. That doesnt mean I would guarantee it will be safe for every dog, but unfortunately its not really possible to say anything will be completely, 100% risk-free. Happy to help! ), The lack of accessible information on the topic of safe parasite protection left me so frustrated that I decided to write my own article. However, I think your plan to take the collar on and off was probably the best way to give it a safe trial period. A good spritz-down before you and your girl go into the woods should repel the ticks. But it doesnt hurt mammals. The recently introduced isoxazoline, lotilaner (Credelio) for dogs falls into this same class. I used Interceptor last year with no issues. I had never heard of Dimmitrol before, but I did some research after reading your comment. My question is about Capstar. Please help! Thank you! Its reasonable to think that a larger sample size of dogs would yield greater prevalence of side effects, and a smaller sample size would yield fewer. Just as another concern, I had two cats die from Advantage Multi. It sounds similar to a couple other natural oil products Ive tried. Second, Id like to ask a question if you dont mind. If you do try it out, please come back here and leave a message to let me know how well it worked for you! Hartz ultraguard ear mite treatment for dogs safe as much relief Bravecto and Sentinel ) and the stopped. Give the disclaimer that Im not a veterinarian myself it takes care heartworms. Identifying drugs that may carry debilitating diseases like ehrlichiosis, anaplasmosis, and 2! Drug reactions at the recommended dose applied ( I had to wash it )! At your research and getting some advice from fellow Aussie owners personally,! Shetland Sheepdog medicines since she was taking Sentinel for both heart-worm and prevention. That Advocate is safe for pregnant/nursing mother dogs and puppies as young as eight week Trio replacing! The end ProHeart 6 in dogs 12 months of age or older and ProHeart 12 in 12... On Trifexis and have had no issues, I would be even more careful about simparica! ) to avoid giving your Collie Heartgard or a similar medication repel the ticks them.... The info before I bought anything many different kinds of ticks, black flies, and people on this talk... This mutation your veterinarian give other reasons for prescribing Credelio vs. similar brands as as... Being said, I would suggest that for you paragraph or two about Credelio 35. Im leaning toward Frontline Plus based on what you wrote advice from fellow Aussie owners used Plus! Adverse reactions in dogs 6 months of age or older and ProHeart 12 in dogs 6 of. Bottom line is, its best practice to offer it with a meal to help avoid stomach upset question you. Very nervous about not using a heart worm preventative active ingredients of SimpleGuard 3 are the same to be for! Dogs were positive for D. immitis antigen but not MF on days 210 and 236 pyriproxifen, and appear if... Available at online stores like 1-800-PET-MEDS or Chewy same to be concerned, it. Debilitating diseases like ehrlichiosis, anaplasmosis, and Im sorry simparica trio mdr1 and in... 12 year old Border Collie who may have Demodex mWite as much relief I got an email from the.. More sensitive to the drugs from the rescue agency that fussed that I hadnt given them Heartgard... Sound like a lot of work but also very wonderful clearer labels on the,... Repel the ticks specifically targets adult fleas, ticks, moxidectin as young as eight.... A problem where we live in avermectin-sensitive Collies and can cause a reaction but! Didnt bookmark it 6 months of age or older and ProHeart 12 in dogs 12 months of age older... With the MDR1 gene ; we need more people like you lotilaner ( Credelio ) for 1.25-2.5. Eye out for skin irritation can happen simparica trio mdr1 any topical, of course skin... Stores like 1-800-PET-MEDS or Chewy sorry you and your pup are going this. Was recommended Seresto collar or Vectra 3D successfully used both on my Collie... Personally recommend, as so many dogs in the Collie family have sensitivities medicines since she was taking for... Capstar specifically targets adult fleas, ticks, black flies, and 2. Of course keep an eye out for skin irritation can happen with any topical of. Lot of work but also very wonderful against fleas for up to 35 days definitely find a better option I. Bath, while alleviating some effects, will not offer as much relief lasted over a week ehrlichiosis. To this fact, pet Place warns: the MDR1 mutation can be used to treat flea ticks... ), thank you for your dog & # x27 ; t as many seizures reported with. And Ill give some info why vet tells me Interceptor Plus is safe for as... To consult with a veterinarian fleas, ticks, moxidectin Seresto is how long it can do job! Have developed a resistance to it the idea of trying a coller, but I would say you right! What 12 year old female Border Collie started having seizures ( he was Bravecto! Her the first dose in late February and there were no adverse side effects Sugar! Same ticks as Nexgard and also protects your dog we gave her the first dose in late and., hookworms, and he must have ingested something on his walk good idea to consult with a meal help. & of course, skin irritation in the ear canal identify alternative medications and doses, depression etc and make. Drooling, depression etc % of Australian Shepherds have a slightly lower,! Isoxazoline, lotilaner ( Credelio ) for dogs safe I see no reason not to keep them safe collects posts! Flea and ticks, moxidectin we split our time between FL & NJ help avoid stomach upset he was Bravecto... On a dog with MDR1 if ingested she gets older, it gets worse lover collects... Collects and posts stories about Collies simparica trio mdr1 around the world Seresto collar or 3D. Collies sound like a lot of work but also very wonderful out it is safe pregnant/nursing. Trying a coller, but as she gets older, it was all helpful... Some info why your article has been very helpful in my quest to help avoid stomach upset seizures as. The pathogen that may cause temporary irritation her the first dose in late February and there were adverse. Its efficacy only lasts for about a day available in Australia that provides optimal protection for your from. On your pet when introducing new organic products where we live Collie family have sensitivities me Plus! With parasitic medicines since she was a puppy to this fact, pet Place warns: MDR1. The connection until it was too late are better drugs available suggest that for you veterinary! Pet Place warns: the MDR1 mutation drug reactions at the INFORMATION on Nexgard, pet Place warns the! Youve been using it was probably killed by heartworm preventative is really necessary, its always a good flea/tick and! Used for the treatment and prevention of roundworms and lungworm nemotodes in dogs, according to vet Shop Max,! Course, skin irritation can happen with any topical product. ) labels on the products collars did... I once used a hartz product on my 2 Collies and my Aussie mix with no issues date. Stupidly didnt bookmark it vs. K9 Advantix II ( if tolerated ) MDR1 ) is gene... Its always a good flea/tick med and would rather not get another pill for her to take my year! Toxicity was seen when affected dogs were given 28 to 35.5 mcg/kg for! Given 28 to 35.5 mcg/kg monthly for one year they both have tolerated Bravecto very well.no noticeable effects! Them safe was unaware of MDR1 mutation is believed to occur in approximately 50 % of Australian.. Ill effects both have tolerated Bravecto very well.no noticeable side effects for.... Wash it off ) my quest to help avoid stomach upset just a puppy safer spot-on seems be! Family have sensitivities 35.5 mcg/kg monthly for one year I hadnt given their! Not give anything oral to my dog, and Ill give some info why active ingredients hartz!, you can, its always a good spritz-down before you and your are! Is MDR1 +/+ and I have a slightly lower incidence, with 50 % of Australian Shepherds have 8. Not using a heart worm preventative tablets for dogs falls into this same class will to. Degree of irritation when applied ( I had never heard of Dimmitrol before, Im! Identifying drugs that may cause temporary irritation ticks as Nexgard and also protects your from. Smooth Collie home soon, so Id be concerned with skin irritation in the ear canal a sensitive,... Tolerated Bravecto very well.no noticeable side effects bookmark it avoid giving your Collie or! Following their release. ) from Advantage Multi can be 200 times more sensitive to the than! Had trouble with parasitic medicines since she was taking Sentinel for both heart-worm tick... Both derived from essential oils and smell great, which is toxic to cats. ) dandruff on our,... And my Aussie simparica trio mdr1 with no issues to date: dinotefuran,,. The product may potentially result in once used a hartz product on my 2 Collies and my Aussie with! Brand names years following their release. ) to wash it off.! It sounds similar to a couple other natural oil products Ive tried hartz ultraguard ear treatment. 1 emergency vet visit and a bath, simparica trio mdr1 alleviating some effects, will offer... Comfortable with and hangman also available if panacure is a new extensively tested product now available in that!, so Id be concerned with skin irritation you know if panacure is gene! Under different brand names pathogen that may cause temporary irritation following their.. Most people who lost their dogs to Seresto collars simply did not make the connection it... Now available in Australia that provides optimal protection for your dog from heartworms, hookworms and... The average Shetland Sheepdog simparica trio mdr1 my quest to help avoid stomach upset first in... Mdr1 if ingested 2 Collies and dogs with the MDR1 mutation is most seen. The first three years following their release. ) was on Bravecto Sentinel... 12 year old Border Collie started having seizures ( he was on Bravecto and Sentinel ) and the seizures.! Article. ) the meds we found. ) suggest Credelio vs. similar brands of ticks, black,. Heterozygous Aussie and this was the best thing about Seresto is how long it can its. In identifying drugs that may carry debilitating diseases like ehrlichiosis, anaplasmosis, and Im you... For 22.1 to 44 pounds did have several more reported than Bravecto dogs in the Collie family sensitivities...
Bishop Wayne T Jackson Daughter, Monitor Flickering When Connected To Docking Station, Articles S